Isolating and purifying hemoglobin variants can be a real challenge. Traditional reversed-phase chromatography often falls short of achieving optimal analyte resolution from complex mixtures, while demanding applications and low-quality columns introduce variability into experimental results, bringing research to a halt.
PolyLC provides innovative chromatography solutions, including cation-exchange columns and a portable HPLC instrument, that are designed to overcome complex separation challenges. Our high-quality products are carefully manufactured to provide consistent performance, and our experienced team can help you design custom solutions for any application.
Learn more about how PolyLC can help you achieve optimal analyte resolution and overcome Hb variant analysis challenges.
Our PolyCAT A™ ion exchange columns are designed to provide exceptional performance for the separation of charged molecules, including hemoglobin variants. These columns offer high resolution, selectivity, and reproducibility, ensuring reliable results for your research. Whether you need to resolve HbE from A2, achieve more precise quantitation of HbA1c levels, or quantify uncommon variants like HbE and HbD, PolyCAT A™ delivers consistent and accurate results.
One of the key advantages of PolyCAT A™ is its versatility. The same column can be used for both QS analysis and HR screening, allowing you to easily switch between different analytical needs without needing to change columns. This flexibility saves time and resources, streamlining your workflow and improving efficiency.
FEATURED PUBLICATION:
Read how researchers used CRISPR-Cas9 gene editing to increase fetal hemoglobin (HbF) in blood cells, potentially offering a new treatment for sickle cell disease and β-thalassemia.
PolyCAT A™ was critical in this study, accurately measuring HbF levels and demonstrating the effectiveness of this gene-editing technique.
The SmartLC™ is a portable and versatile HPLC system designed to provide high-quality hemoglobin variant analysis in the lab or the field. Its compact size and robust performance make it ideal for research, clinical diagnostics, and point-of-care testing.
Contact us to discuss your chromatography needs and let us help you find the optimal solution for your specific application.
© Copyright 2024 PolyLC Inc.